FluNexus

Data Preprocessing

Data preprocessing for HI and HA1.        

Antigenic Prediction

Sequence-based tools for online antigenic prediction with practical guidance.        

Antigenic Map

Mapping the antigenic evolution of influenza A virus.

Antigenic Cluster

Mapping the antigenic relationship of influenza A virus.

Tutorial

Guidelines for data input, tool usage, and result interpretation.

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FluNexus is a first-of-its-kind, one-stop-shop web platform designed to facilitate the prediction and visualization of antigenic relationships in influenza A viruses. It provides:

  • A data preprocessing module for HA1 and HI data spanning the H1, H3, and H5 subtypes.
  • Online antigenic prediction module utilizing ten state-of-the-art antigenic prediction tools and practical guidance based on a comparative evaluation.
  • A visualization module for mapping antigenic evolution of influenza A viruses, incorporating a novel manifold-based method for antigenic cartography.